A Clinician’s Guide to Peptides in 2026
A Practical Framework for Navigating the Evolving World of Peptide Therapies.
Secure. Instant. Clinician-focused.
Patients
are asking about peptides.The science
is evolving rapidly.Regulatory
guidance continues to shift.Yet most clinicians were
never formally trained to evaluate peptide therapies.This guide was created to help clinicians navigate that complexity with greater clarity, confidence, and clinical rigor.
As a result, many healthcare professionals find themselves caught between patient demand, emerging evidence, social media claims, and an increasingly complex therapeutic landscape.
WHAT MAKES THIS GUIDE DIFFERENT?
Rather than teaching clinicians what to prescribe, we focus on a systematic framework for evaluating whether a peptide should be considered in the first place.
Most peptide education focuses on individual peptides
This guide focuses on clinical reasoning and individuals who use them
The goal is not memorization. The goal is developing a repeatable decision-making process that can be applied across peptide categories, patient presentations, and future therapies.
INTRODUCING THE
B-CLOSE FRAMEWORK™
A practical clinical reasoning framework designed to help clinicians evaluate peptide therapies through the lens of biology, evidence, patient context, outcomes, and safety.
By the end of this guide, you will understand how to:
- Assess whether a peptide is mechanistically appropriate for a patient's presentation
- Identify gaps in diagnosis and conventional care before considering peptide therapy
- Apply a structured framework to clinical decision-making
- Define meaningful outcomes and monitoring strategies
- Establish clear success metrics and stopping criteria
- Navigate an evolving therapeutic landscape with greater confidence
WHAT YOU WILL RECEIVE
Digital PDF Guide
Practical decision-making tools
Safety and regulatory considerations
Overview of major peptide categories
Quick-reference clinical resources
Real-world case examples
Clinical reasoning framework for peptide evaluation
WHO THIS GUIDE IS FOR
Physicians
Nurse Practitioners
Physician Assistants
Pharmacists
Physical Therapists
Licensed healthcare professionals
COURSE DIRECTORS
Dr. Jyothsna Giri
Kumpf
MD, MBA
Former Mayo Clinic course director, physician - educator, focused on helping clinicians translate emerging science into confident, evidence-informed care. Over 15 years of clinical insight, digital learning strategy, and product leadership, advancing education delivery and professional development.
Dr. Adrijana
Kekic
PharmD, MHI, MSci, BCACP
Former Mayo Clinic in Arizona Pharmacogenomics PGx Clinical Pharmacy Specialist, Assistant Program Director, and lecturer in psychopharmacology and precision medicine. Over 20 years of experience translating emerging science into innovative and practical clinical decision-making.
THIS IS JUST THE BEGINNING
This guide serves as the foundation for a larger peptide education ecosystem currently in development, including advanced case-based training, clinical implementation tools, and future educational programs.
Build a Framework
Not More Protocols
Peptides will continue to evolve.
The ability to evaluate them systematically will remain valuable, regardless of which therapies or peptides emerge next.
Get Your Guide
to Stay Ahead
Secure. Instant. Clinician-focused.
Frequently Asked Questions
Everything you need to know before getting started.
This guide was developed for licensed healthcare professionals, healthcare trainees, and other individuals seeking a structured approach to understanding peptide therapies.
No. The content is written from a clinician-focused perspective and is designed to support healthcare education and clinical reasoning.
No. The guide focuses on clinical reasoning, evaluation frameworks, and evidence-informed decision-making rather than specific prescribing recommendations. More on prescribing recommendations in our upcoming course.
Most readers can review the guide in approximately 1–2 hours, though many return to the framework and clinical tools as ongoing references.
Yes. This guide serves as the foundation for future peptide education, including advanced case-based training and clinical implementation resources.
